Prof. Dr. Ingmar Glauche
© Ingmar Glauche
Group leader
NameMr Prof. Dr. rer. med. Ingmar Glauche
Deputy Institute Director
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Ingmar Glauche is deputy head of the Institute for Medical Informatics and Biometrics and leads the research group for Theoretical Stem Cell Biology. He is the coordinator of institute's teaching activities. Professor Dr. Glauche represents the Medical Faculty as an elected member of the extended senate of TU Dresden. Additionally, Professor Dr. Glauche serves as a voluntary conflict mediator at TU Dresden.
Prof. Dr. Glauche’s research focus covers the following areas:
Hematopoietic stem cell aging:
- Clonal competition and clonal dominance
- Age-related changes in the polarity of HSC divisions
Theoretical concepts of stem cell organization:
- Proliferation- and differentiation control of haematopoietic stem cells
- Clonal competition phenomena
- Cell fate regulation of mouse embryonic stem cells
Disease and treatment models:
- Chronic and acute myeloid leukaemia
- Conceptual understanding of inherited bone marrow failure syndromes
- Gene therapeutic approaches
Statistical analysis of dynamic processes and structures
- Image analysis and single cell tracking
- Analysis of cellular genealogies
Clonal tracking
- Genetic barcoding
- Analysis of multiple integrations
Publications
2025
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Subtle changes in clonal dynamics: Challenges in quantifying the slow expansion of small hematopoietic stem cell clones, Oct 2025, In: Computers in biology and medicine. 197, Part B, 111079Electronic (full-text) versionResearch output: Contribution to journal > Research article
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A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision, 4 Sep 2025, In: Molecular cell. 85, 17, p. 3241-3255.e11Electronic (full-text) versionResearch output: Contribution to journal > Research article
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The impact of donor and recipient age on post-transplantation clonality in murine hematopoiesis, 4 Sep 2025, In: Stem Cells. 43, 12, sxaf059Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Speeding up for lympho-myeloid differentiation, 7 Aug 2025, In: Blood. 146, 6, p. 650-652, 3 p.Electronic (full-text) versionResearch output: Contribution to journal > Comment/Debate
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Mathematical modeling unveils the timeline of CAR-T cell therapy and macrophage-mediated cytokine release syndrome, Apr 2025, In: PLOS computational biology. 21, 4, e1012908Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Math models expose myeloid bias mechanisms in hematopoiesis, 20 Mar 2025, In: Blood. 145, 12, p. 1231-1232, 2 p.Electronic (full-text) versionResearch output: Contribution to journal > Comment/Debate
2024
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Scientific competence during medical education - insights from a cross-sectional study at a German Medical School, Dec 2024, In: BMC medical education. 24 (2024), 1, 14 p., 590Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche, 21 Mar 2024, In: Leukemia. 38, 5, p. 936-946, 11 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
2023
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Continuous therapy response references for BCR::ABL1 monitoring in pediatric chronic myeloid leukemia, 24 Oct 2023, In: Scientific reports. 13, 1, 10 p., 18199Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Data integration between clinical research and patient care: A framework for context-depending data sharing and in silico predictions, 15 May 2023, In: PLOS digital health. 2, 5, 17 p., e0000140Electronic (full-text) versionResearch output: Contribution to journal > Research article
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