Prof. Dr. Ingmar Glauche
© Ingmar Glauche
Group leader
NameMr Prof. Dr. rer. med. Ingmar Glauche
Deputy Institute Director
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Ingmar Glauche is deputy head of the Institute for Medical Informatics and Biometrics and leads the research group for Theoretical Stem Cell Biology. He is the coordinator of institute's teaching activities. Professor Dr. Glauche represents the Medical Faculty as an elected member of the extended senate of TU Dresden. Additionally, Professor Dr. Glauche serves as a voluntary conflict mediator at TU Dresden.
Prof. Dr. Glauche’s research focus covers the following areas:
Hematopoietic stem cell aging:
- Clonal competition and clonal dominance
- Age-related changes in the polarity of HSC divisions
Theoretical concepts of stem cell organization:
- Proliferation- and differentiation control of haematopoietic stem cells
- Clonal competition phenomena
- Cell fate regulation of mouse embryonic stem cells
Disease and treatment models:
- Chronic and acute myeloid leukaemia
- Conceptual understanding of inherited bone marrow failure syndromes
- Gene therapeutic approaches
Statistical analysis of dynamic processes and structures
- Image analysis and single cell tracking
- Analysis of cellular genealogies
Clonal tracking
- Genetic barcoding
- Analysis of multiple integrations
Publications
2018
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Correction: Incidence of Diabetic Ketoacidosis of New-Onset Type 1 Diabetes in Children and Adolescents in Different Countries Correlates with Human Development Index (HDI): An Updated Systematic Review, Meta-Analysis, and Meta-Regression, Mar 2018, In: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. Vol. 50. p. e2Electronic (full-text) versionResearch output: Contribution to specialist publication > Corrections (errata and retractions)
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Incidence of Diabetic Ketoacidosis of New-Onset Type 1 Diabetes in Children and Adolescents in Different Countries Correlates with Human Development Index (HDI): An Updated Systematic Review, Meta-Analysis, and Meta-Regression, Mar 2018, In: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 50, 3, p. 209-222, 14 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
2017
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MAGPIE: Simplifying access and execution of computational models in the life sciences, Dec 2017, In: PLoS Computational Biology. 13, 12, p. e1005898Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Genetic Barcodes Facilitate Competitive Clonal Analyses In Vivo, Oct 2017, In: Human Gene Therapy. 28, 10, p. 926-937, 12 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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A mathematical modeling approach towards immunological control of minimal residual disease in CML patients, Sep 2017, p. S103Electronic (full-text) versionResearch output: Contribution to conferences > Poster
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Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion, 14 Jul 2017, In: Molecular Cancer. 16, 1, 120Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification, 30 May 2017, In: Cell Reports. 19, 9, p. 1953-1966, 14 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Limitations and challenges of genetic barcode quantification, 3 Mar 2017, In: Scientific Reports. 7, 43249Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy, Feb 2017, In: Haematologica. 102, 2, p. e39-e42Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny, 17 Jan 2017, In: The EMBO journal. 36, 2, p. 151-164, 14 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article