Prof. Dr. Ingmar Glauche
© Ingmar Glauche
Group leader
NameMr Prof. Dr. rer. med. Ingmar Glauche
Deputy Institute Director
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Ingmar Glauche is deputy head of the Institute for Medical Informatics and Biometrics and leads the research group for Theoretical Stem Cell Biology. He is the coordinator of institute's teaching activities. Professor Dr. Glauche represents the Medical Faculty as an elected member of the extended senate of TU Dresden. Additionally, Professor Dr. Glauche serves as a voluntary conflict mediator at TU Dresden.
Prof. Dr. Glauche’s research focus covers the following areas:
Hematopoietic stem cell aging:
- Clonal competition and clonal dominance
- Age-related changes in the polarity of HSC divisions
Theoretical concepts of stem cell organization:
- Proliferation- and differentiation control of haematopoietic stem cells
- Clonal competition phenomena
- Cell fate regulation of mouse embryonic stem cells
Disease and treatment models:
- Chronic and acute myeloid leukaemia
- Conceptual understanding of inherited bone marrow failure syndromes
- Gene therapeutic approaches
Statistical analysis of dynamic processes and structures
- Image analysis and single cell tracking
- Analysis of cellular genealogies
Clonal tracking
- Genetic barcoding
- Analysis of multiple integrations
Publications
2026
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Therapeutic Drug Monitoring of Imatinib in Paediatric Chronic Myeloid Leukaemia: Towards Practical Implementation and Interpretation of Measured Plasma Concentrations, Jul 2026, In: Clinical pharmacokinetics. 65, 7, p. 1013–1026, 14 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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[18F]Fluorodeoxyglucose-PET/MRI-based response assessment following BCMA-directed CAR-T-cell therapy with ciltacabtagene autoleucel in relapsed/refractory multiple myeloma, 21 May 2026, In: HaematologicaElectronic (full-text) versionResearch output: Contribution to journal > Letter
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Scientific education in German medical schools: nationwide cross-sectional study reveals student needs and gaps, 2 May 2026, In: BMC medical education. 26, 1, 729Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Long-term clonal analysis using stochastic models reveals heterogeneity and quiescence of hematopoietic stem cells, 31 Mar 2026, In: Computers in biology and medicine. 208, 10 p., 111650Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Dynamics of BCR::ABL1 transcript levels and clinical outcomes after switch to second-line therapy in pediatric chronic myeloid leukemia, Mar 2026, In: HemaSphere. 10, 3, 6 p., e70347Electronic (full-text) versionResearch output: Contribution to journal > Letter
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Sequential BCR::ABL1 evaluation during dose de-escalation in peripheral blood is more predictive of TFR success than single assessment at dose de-escalation in either peripheral blood or bone marrow, Feb 2026, In: Leukemia. 40, 2, p. 459–463, 5 p.Electronic (full-text) versionResearch output: Contribution to journal > Letter
2025
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Prognostic Value of Multicolor-Flow Cytometric Measurable Residual Disease Detection in Acute Myeloid Leukemia Prior to Allogeneic Hematopoietic Cell Transplantation: Potential Role of HLA-DR, Dec 2025, In: Clinical Lymphoma, Myeloma and Leukemia. 25, 12, p. e1108-e1119.e2Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Tumor-Tissue Boundaries as Instructive Interfaces in Breast Cancer Cell Invasion, Nov 2025, In: Advanced Science. 12, 44, e09249Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Predicting treatment-free remission in chronic myeloid leukemia patients using an integrated model of tumor-immune dynamics, 16 Oct 2025, In: npj systems biology and applications. 11, 1, 115Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Impact of exposure frequency on disease burden of the common cold - A mathematical modeling perspective, Oct 2025, In: PloS one. 20, 10, e0334527Electronic (full-text) versionResearch output: Contribution to journal > Research article